Destinies intertwine in a tale of Gothic horror and intrigue set in the seedy underbelly of Philadelphia. A broken man, Carl Spencer embarks on a vengeance-fueled quest in the pursuit of the vampire that murdered his wife. His target: Demetrius, a creature torn between his allegiance to his master and his own thirst for blood. Spencer's journey brings him to two sisters, victims of a dark family secret. The fates of all become tied to an insidious plot to resurrect an ancient vampire witch. 'Lifeblood' is a suspenseful neo-noir, featuring music from some of Philadelphia's hottest Goth/industrial bands including a special appearance by Carfax Abbey.